AbioSUS Single-Use Bioreactor

Applitech's AbioSUS replicates traditional stirred-tank bioreactor conditions to ensure seamless transitions across research, development, and production scale. 

This system supports a wide range of upstream cell culture applications for antibodies, vaccines, and therapies through standard sizes ranging from 50L to 2000L and further customization options.

Key Components

Bag Holder

Design Features

  • Top-mounted motor drive: Quick, convenient assembly/disassembly
  • Large single-door holder: Easy culture bag loading/unloading
  • Full double-layer jacket: uniform thermal control
  • C6-grade load sensors: High-accuracy weight measurement
  • Stainless-Steel Bag Holder
  • Weighing Sensor Support Bracket
  • Door with Observation Window
  • Sensor Operation Area
  • 50-2000 Liters Working Volume

IDS.DS Controller

  • 18.5/21.5-inch HMI display
  • Anti-mistouch + screen lock
  • User access control: 5 levels with permissions & audit trail
    • (View, Operator, Engineer, Supervisor, Administrator)
  • Multi-loop control: Temperature, agitation, pH, DO
  • Software-controlled bottom aeration paths
  • Advanced cascade settings for parameter control
  • Device integration: Pumps, MFCs, balances
  • Customizable for client-specific configuration
  • Small footprint and space-saving
  • Built-in UPS power supply

Culture Bags

Design Features

  • Flexible sensing: Supports reusable & single-use pH/DO
  • Dual aeration system: 0.8 mm macro-bubble + 150 µm micro-bubble
  • Enhanced mass transfer: Higher KLa, better pH control, reduced foam
  • Customizable aeration ports: Types and specifications configurable
  • Integrated inlet and outlet filters to avoid additional sterile connection
  • Two marine blade impellers

Material Features

  • 7-layer co-extruded film (320 µm) for high strength and durability
  • Animal-component-free materials
  • ULDPE inner layer for superior biocompatibility and flexibility
  • Sterile, pyrogen-free, and highly gas-tight
  • Compliant with USP Class VI and ISO 10993 standards
  • Full material certification and traceability
  • Customizable designs for specific process needs