CrystalEYES Crystallization Monitoring System
CrystalEYES is an advanced crystallization monitoring system by H.E.L, designed to measure turbidity, temperature, and optional pH during crystallization processes. It enables real-time detection of dissolution and nucleation points, supporting accurate crystallization analysis and process development. With scalable probe options and flexible upgrades, CrystalEYES provides a versatile solution for crystallization monitoring across all laboratory scales.
Key Highlights:
Crystallization Monitoring and Analysis
CrystalEYES enables chemists to monitor crystallization processes in real-time, providing clear identification of dissolution and nucleation events to support improved understanding and control of crystallization behavior — critical for determining the quality, performance, and manufacturability of chemical and pharmaceutical products.
Flexible Measurement Capabilities
The system measures turbidity and temperature as standard, with optional pH monitoring where required. This combination of parameters provides a comprehensive view of crystallization processes, enabling more accurate data collection and analysis.
Scalable Across All Development Stages
CrystalEYES supports scales ranging from small test tubes of around 3 ml to large vessels exceeding 10 liters. Probes are available in 316 stainless steel and Hastelloy, ensuring broad chemical compatibility. Scaling between applications requires only a probe change, with no modification to the system electronics or software.
Integrated Data Logging and Analysis
All experimental data is automatically recorded in CSV format, allowing easy transfer to Excel or other analysis tools. This ensures efficient data handling and supports rapid interpretation of crystallization results.
Upgradeable Control and Multi-Reactor Monitoring
CrystalEYES can be upgraded to include full process control, enabling precise management of heating, cooling, stirring, and liquid dosing. Multi-channel configurations are also available, allowing simultaneous monitoring and control of multiple reactors for increased throughput and efficiency.
Turbidity
CrystalEYES utilizes H.E.L's proprietary turbidity sensors and WinISO Control software to detect solubility and recrystallization points from sharp changes in signal, displayed graphically in real-time. A Near-Infrared (NIR) source sends light through the solution and back to a detector via a mirror, measuring turbidity as a function of light intensity. Probes are constructed in hard-wearing Hastelloy, with the light source and detector built into each probe. At just 5 mm in diameter, up to 8 probes can be operated simultaneously and are suitable for the smallest of vessels.
Key Features:
- Temperature and turbidity probes chosen specifically for your application
- Electronics and PC with data handling software
- pH monitoring available as an option
- Maximum temperature: 200°C; Maximum working pressure (MWP): 10 bar at 25°C
Ease of Use:
- Insert the probes into your vessel
- Heat and cool your solution
- Data is automatically displayed and recorded
Data Handling:
- Real-time data display and capture
- Data is automatically saved to a data file
- Data is readily exported to Excel for analysis